HealthDay News — Morning home blood pressure (HBP) is a better predictor of stroke and coronary artery disease (CAD) events than clinic blood pressure, according to research published in the Journal of the American College of Cardiology.

Kazuomi Kario, MD, from the Jichi Medical University School of Medicine in Japan, and colleagues used data from the Home blood pressure measurement with Olmesartan Naive patients to Establish Standard Target (HONEST) blood pressure study to examine the correlation between morning HBP and the incidence of stroke and CAD events.

The researchers identified 127 stroke events and 121 CAD events in 21 591 treated hypertensive patients. Patients with morning home systolic blood pressure (HSBP) ≥145 mm Hg had significantly higher incidence of stroke events compared to those with HSBP <125 mm Hg; stroke incidence was also higher for patients with clinic systolic blood pressure (CSBP) ≥150 mm Hg versus <130 mm Hg. Prediction of stroke events was similar for HSBP and CSBP. Patients with morning HSBP ≥145 mm Hg versus <125 mm Hg had elevated incidence of CAD events, as did those with CSBP ≥160 mm Hg versus <130 mm Hg. Prediction of CAD events was more robust with morning HSBP than CSBP.

“Morning HBP is a strong predictor of future CAD and stroke events, and may be superior to clinic BP in this regard,” the authors write.

Several authors disclosed financial ties or were employed by Daiichi-Sankyo Co., which funded the study.


Kario K, Saito I, Kushiro T, et al. Morning Home Blood Pressure Is a Strong Predictor of Coronary Artery Disease: The HONEST Study. J Am Coll Cardiol. 2016;67(13):1519-1527. doi:10.1016/j.jacc.2016.01.037.