Oral anticoagulants for stroke prevention in atrial fibrillation (afib) gained a substantially enlarged population from new guidelines that gave a “near-universal indication for women and for patients older than 65,” researchers found.

The 2014 guidelines boosted the proportion of patients in a national afib registry who would have been recommended for oral anticoagulants to 90.8%, compared with 71.8% under the 2011 guidelines (P<0.001), Emily O’Brien, PhD, of the Duke Clinical Research Institute in Durham, N.C., and colleagues found.

Two-thirds of all afib patients not previously recommended for oral anticoagulants would be under the 2014 revision to the American Heart Association, American College of Cardiology, and Heart Rhythm Society afib guidelines.


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