Among pediatric patients with cerebral venous thrombosis, treatment with rivaroxaban or standard anticoagulants resulted in a similarly reduced risk for recurrent VTE or bleeding.
In a study of patients with intracerebral hemorrhage, those with baseline creatinine levels of 110 µmol/L or higher and who received higher doses of nicardipine, a hypertensive drug, had an increased risk for acute kidney injury.
Among patients with unruptured brain arteriovenous malformation, medical management alone is superior to its combination with interventional therapy for prevention of death or symptomatic stroke in the long term.
Administration of DOAC in combination with an antiplatelet agent may reduce the risk for hemorrhagic and embolic events in patients with nonvalvular atrial fibrillation following carotid artery stenting.