HealthDay News — Introduction of a guideline-based protocol significantly increases compliance for prevention of venous thromboembolism (VTE), according to a brief report published in the Canadian Journal of Cardiology.

Mehrdad Golian, MD, from the University of Manitoba in Winnipeg, Canada, and colleagues examined whether a guideline-based protocol improves VTE guideline compliance based on 10 single-day audits of a cardiology inpatient unit. Four hundred twenty patients at high risk for VTE were included (median age, 66 ± 14 years).

The researchers found that 36% of patients were not receiving VTE prophylaxis before the protocol, compared with 26% after the protocol (P = 0.024).

“There is a high rate of noncompliance with accepted guidelines for the prevention of VTE,” the authors write. “The introduction of a guideline-based protocol significantly increased compliance. However, a substantial proportion of patients at high risk for VTE still did not receive prophylaxis.”


  1. Golian M et al. Can J Cardiol. 2015; doi:10.1016/j.cjca.2015.05.023.