The role of vascular closure devices (VCD) for the achievement of hemostasis in patients undergoing transfemoral coronary angiography remains controversial.

Study researcher Stefanie Schulz-Schüpke, MD, of the Deutsches Herzzentrum München, Technische Universität, in Munich, and colleagues compared outcomes with the use of two hemostasis strategies after diagnostic coronary angiography performed via transfemoral access — a VCD-based strategy with 2 types of devices, an intravascular device and an extravascular device, vs. standard manual compression. 

The primary hypothesis to be tested was that femoral hemostasis achieved through VCD is noninferior to manual compression in terms of vascular access–site complications.

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