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TRUMENBA
Vaccines
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Drug Name:

TRUMENBA Rx

Generic Name and Formulations:
Neisseria meningitidis recombinant lipidated factor H binding protein (fHBP) variants 120mcg of Group B (subfamily A + subfamily B); per 0.5mL; susp for IM inj; contains polysorbate 80.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for TRUMENBA:

N. meningitidis serogroup B immunization.

Adults and Children:

<10yrs: not established. Give by IM inj into deltoid muscle of upper arm. 10–25yrs: 0.5mL. 3-dose series: give at 0, 1–2, and 6mos. 2-dose series: give at 0 and 6mos; if 2nd dose given too early, give a 3rd dose ≥4mos after the 2nd dose.

Contraindications:

Severe allergic reaction after a previous dose of Trumenba.

Warnings/Precautions:

Not interchangeable with other MenB vaccines. Have epinephrine inj readily available. Immunosuppressed. Complement deficiency. Eculizumab therapy. Elderly. Pregnancy. Nursing mothers.

Interactions:

Concomitant other vaccines: see full labeling.

Pharmacological Class:

Meningitis vaccine.

Adverse Reactions:

Inj site pain, fatigue, headache, muscle pain, nausea; syncope.

How Supplied:

Single-dose prefilled syringe—5, 10

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