XOPENEX CONCENTRATE Rx
Generic Name and Formulations:
Levalbuterol (as HCl) (single-isomer albuterol) 1.25mg/0.5mL; per vial; soln for inhalation via nebulization after dilution; preservative-free.
Indications for XOPENEX CONCENTRATE:
Initially 0.63mg by nebulization 3 times daily at 6–8 hr intervals; may increase to 1.25mg 3 times daily.
<6yrs: not established. 6–11yrs: 0.31mg by nebulization 3 times daily; max 0.63mg 3 times daily.
Do not exceed recommended dose. Monitor for increased need; if inadequate control, reevaluate and consider adding an antiinflammatory (eg, corticosteroids). Sensitivity to sympathomimetics. Discontinue if paradoxical bronchospasm or cardiovascular effects occur. Cardiovascular disorders (esp. coronary insufficiency, arrhythmias, hypertension). Seizure disorders. Diabetes. Hyperthyroidism. Renal impairment; monitor (esp. in elderly). Elderly. Labor & delivery. Pregnancy. Nursing mothers.
Avoid within 2 weeks of MAOIs, tricyclic antidepressants. Avoid other short-acting sympathomimetic aerosol bronchodilators, epinephrine. Antagonized by β-blockers. Caution with other drugs that may lower serum potassium (eg, diuretics). Monitor digoxin.
Accidental injury, bronchitis, dizziness, pain, pharyngitis, rhinitis, vomiting; paradoxical bronchospasm, hypersensitivity reactions, cardiovascular effects, hypokalemia.
Vials (YES); HFA (NO)
Inhaler w. actuator (80inh)—8.4g, (200 inh)—15g; Soln 0.31mg/3mL, 0.63mg/3mL, 1.25mg/3mL—24 vials; Concentrate 1.25mg/0.5mL—30 vials
Neurology Advisor Articles
- FDA Approves Aimovig for Migraine Prevention
- Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion
- Sports-Related Concussion Outcomes Predicted With Serum Neurofilament Light
- Psychological Therapies May Help Older Adults With Chronic Pain
- Traumatic Brain Injury Linked to Increased Parkinson Disease Risk in Veterans
- Amyloid Positivity Increases Risk for Cognitive Impairment in Dementia-Free Patients
- Valproic Acid-Related Adverse Fetal Outcomes May Be Linked to Placental Effects
- Risk of Dementia Up for Older Adults With Lowest Wealth
- Language Used in Medical Record Can Affect Patient Care
- Mortality in Alzheimer Disease Not Strongly Associated With Antipsychotics